UK Careers

FUJIFILM Diosynth Biotechnologies is hiring a Staff Scientist in Cell Culture R&D and an R&D Analytical Development Lead. The positions are both located in our Billingham, UK (NE area of England) site.


Staff Scientist –  Mammalian Cell Culture R&D Upstream Process Development Lead

We are looking for a  technical leader who can demonstrate a strong track record for the successful development and transfer of mammalian cell culture processes from R&D to cGMP manufacturing. The ideal candidate:

  • Applies scientific and technical experience and business acumen to drive high-quality laboratory work, and deliver well-controlled and characterized upstream manufacturing processes to aggressive timelines. Projects will range from early phase process development to commercial stage biologics manufacture.
  • Provide leadership and direction within the process development sub-group in Mammalian Cell Culture R&D, with line management responsibility.
Education and Experience

Ideally a Ph.D. degree, or significant experience in Biochemical Engineering, Biotechnology, Cell Biology, or related field. 5-10 years’ experience in the biotech/pharmaceutical industry within a mammalian cell culture role and an excellent understanding of the theory and practice of cell culture and process development is required.

Technical Skills Requirements
  • Design, develop and scale up reproducible and robust cGMP compliant mammalian cell culture upstream processes.
  • Provide scientific and technical leadership in the application of Design of Experiments (DoE) and appropriate cell culture scale down models.
  • Experience in: media / feed screening, development, and optimization; feed strategy; process parameter optimization; etc.
  •  Support transfer of existing upstream processes from customers and facilitate process development for / transfer to cGMP manufacturing.
  • Have knowledge and experience with glass, stainless steel and single use fed-batch culture processes, at different scales and with different control systems, for recombinant protein production.
  • Write and revise protocols, procedures, reports and other process related documentation as required to support upstream process development and transfer to cGMP manufacturing operations.
  • Provide strong scientific and technical leadership in the identification, evaluation, and championing of new technologies for upstream process development whilst maintaining and improving established technologies.
  • Demonstrate current knowledge of industry trends, practices and standards.
  • Having knowledge and understanding of process characterization and QbD principles, and of FMEA, is a plus.
Other Competencies
  • Have exceptional customer interface skills.
  • Line management experience.
  • Have excellent oral and written communication skills to build relationships both inside and outside the company.
    • Able to communicate project status with customers and project management.
    • Able to collaborate across different disciplines and sites to influence outcomes, devise strategies, and implement them.
    • Able to represent the department at senior management meetings.
    • Able to interface with the commercial team in order to support commercial activities.
    • Able to engage junior scientists to deliver excellent performances.
  • Have ability to execute complex projects to aggressive timelines with the ability to adapt to rapid changes in project priorities.
  • Have demonstrated experience with managing multiple projects in parallel, including key participation on multi-disciplinary project teams.

R&D Analytical Development Lead

We are looking for a  technical leader who can demonstrate a strong track record for the development /establishment of biologics analytics in R&D and transfer to support cGMP manufacturing. The ideal candidate:

  • Applies scientific and technical experience to drive high-quality laboratory work to support process development and reduce timelines Projects will range from early phase process development to commercial stage biologics manufacture.
  • Provide leadership and direction within the R&D analytical development group , with line management responsibility.
Education and Experience

Ideally a Ph.D. degree, or significant experience (minimum of 5 years) in the area of biologics analytics and an understanding of the theory and practice of analytical development through to method validation.

Technical Skills Requirements
  • Develop, plan, execute and manage analytical activities associated with process development and the support of cGMP manufactures.
  • Responsible for the establishment of analytical methodology from customers to the business
  • Deliver cost effective analytical strategy to meet the appropriate current industry trends and regulatory standards
  • Write and revise protocols, procedures, reports and other analytical related documentation as required to support process development and cGMP manufacturing operations.
  • Maintain a technology foresight on new techniques and equipment for biologics analytics
Other Competencies
  • Customer interface skills.
  • Line management experience.
  • Oral and written communication skills to build relationships both inside and outside the company.
  • Have ability to execute complex projects to aggressive timelines with the ability to adapt to rapid changes in project priorities.
  • Have demonstrated experience with managing multiple projects in parallel, including participation on multi-disciplinary project teams.
  • Have strong organizational skills, including the ability to prioritise personal and direct reports workload.

To Apply

If you would like to join this expanding group and have the skills/knowledge and experience, please email your CV to Emma.